Grants & Fellowships

Competitive funding that supports our research across RNA biology, computational modelling, and therapeutics.

RMODELHeld by Nikolay Shirokikh

ROBUST

Awarded

Medical Research Future Fund · National Critical Research Infrastructure · Chief Investigator

ROBUST is designed to deeply re-engineer mRNA structure and stability while ensuring desired functional activity, so the duration and concentration of a therapeutic mRNA in the body can be tuned and held at the right therapeutic level for the disease being treated.

Announcement

The Evolutionary Landscape of RNA Modification in Mammals

Active

Australian Research Council · Discovery Project · DP250103133 · 2025- · Chief Investigator

Mapping how chemical modifications on RNA have evolved across mammals and what they reveal about gene regulation.

National Therapeutic RNA Platform

Active

Medical Research Future Fund · MRFF · 2024- · Chief Investigator

A national capability to design, produce and test RNA-based therapeutics for Australian patients.

Design of Next-Generation Therapeutic mRNA

Active

Industry-led · Industry-funded research · 2024 · Lead

Engineering messenger-RNA designs to improve the next generation of RNA-based cellular immunotherapies.

Control of Translation in Cancer, Cell Stress Response and Ageing

Completed

NHMRC · Investigator Grant (EL1) · 2020-2024 · Lead

Investigating how cells switch protein synthesis on and off in cancer, stress and ageing.

Dissecting the Role of RNA Modifications in Onco-Ribosomes to Inform New Anti-Cancer Therapies

Completed

Bootes Foundation · Research grant · 2021 · Chief Investigator

Examining how RNA modifications reshape ribosomes in cancer cells to reveal new therapeutic targets.

Elucidating Coding-Region Targets of microRNAs

Completed

NHMRC · Ideas Grant · 2020 · Co-Investigator

Discovering where microRNAs act within the protein-coding regions of messenger RNAs.

Genome-Wide Discovery of Translation Control Mechanisms

Completed

Australian Research Council · Discovery Project · DP180100111 · 2017-2021 · Chief Investigator

Systematically identifying the mechanisms that regulate protein synthesis across the genome.

Mathematical Model to Quantify mRNA Degradation and Dissect its Mechanisms in Plants Using Native RNA Sequencing

Active

CNRS · MITI interdisciplinary programme · 2025- · Lead

A CNRS interdisciplinary project developing statistical methods to measure how fast individual RNA molecules are degraded in plants, using direct RNA sequencing. Held jointly with Nikolay Shirokikh.

COMPASSHeld by Alice Cleynen

IdenTHiC: Identification of Tumour History at the Clone level

Active

Agence Nationale de la Recherche · ANR generic call, panel CE45 · ANR-23-CE45-0030-01 · 2024-2028 · Lead

Reconstructing a tumour's history from sequencing data, inferring when its individual cell lineages arose and how they evolved.

Mathematical Model to Quantify mRNA Degradation and Dissect its Mechanisms in Plants Using Native RNA Sequencing

Active

CNRS · MITI interdisciplinary programme · 2025- · Lead

A CNRS interdisciplinary project developing statistical methods to measure how fast individual RNA molecules are degraded in plants, using direct RNA sequencing. Held jointly with Nikolay Shirokikh.

HSMM-INCA: Hidden Semi Markov Models, Inference, Control and Applications

Active

Agence Nationale de la Recherche · ANR generic call, panel CE40 · ANR-21-CE40-0005 · Co-Investigator

Methods for a class of statistical models in which a system moves between hidden states and stays in each for a variable length of time, covering how to infer those states from data and how to act on them.

Statistics and Machine Learning for Single Cell Genomics

Completed

Agence Nationale de la Recherche · ANR generic call, panel CE45 · ANR-18-CE45-0023-03 · Chief Investigator

Statistical and machine learning methods for genomic data measured one cell at a time.

LIMORD: Longitudinal Integrative Models for Online Relapse Detection

Completed

European Commission · Marie Sklodowska-Curie Actions, Global Fellowship · 2022-2024 · Lead

Statistical models that combine a patient's repeated blood-marker measurements over time to detect relapse as early as possible.

Immune Targeting of Multiple Myeloma

Completed

Institut National du Cancer · PLBio · 2016-2020 · Co-Lead

Statistical modelling of sequencing data to understand how the immune system recognises and targets multiple myeloma cells. Led jointly with Ludovic Martinet.

Non-Redundant Binding of AP-1 Subunits in the Regulation of EMT Gene Expression

Completed

NUMEV and SIRIC, Montpellier · 2021-2022 · Co-Lead

A local project analysing how a family of gene-regulatory proteins jointly controls the genes that let cells change identity and become mobile. Led jointly with Andrew Oldfield.

Full grant details are being confirmed for public listing.